BDBM50535490 CHEMBL4451091

SMILES CN(C)c1ncc(cc1-c1ccc(cc1)S(C)(=O)=O)-c1ccc(O)cc1

InChI Key InChIKey=JUSSLCLDOMYWPZ-UHFFFAOYSA-N

Data  7 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50535490   

TargetTRAF2 and NCK-interacting protein kinase(Human)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50535490(CHEMBL4451091)
Affinity DataIC50: <3.16E+4nMAssay Description:Inhibition of human full length TNIK in HEK293 cells co-transfected with full length SMAD1 incubated for 2 hrs by ELISAMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetTRAF2 and NCK-interacting protein kinase(Human)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50535490(CHEMBL4451091)
Affinity DataIC50:  3.98E+3nMAssay Description:Inhibition of human full length TNIK(1-1360)-G5-Avi-6His-Flag expressed in baculovirus-infected sf21 cells using His6-SMAD1 as substrate preincubated...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetTRAF2 and NCK-interacting protein kinase(Human)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50535490(CHEMBL4451091)
Affinity DataIC50:  3.98E+3nMAssay Description:Inhibition of human 6His-TEV-TNIK(1 to 325) expressed in baculovirus-infected sf21 cells using LRRKtide as substrate preincubated for 30 mins followe...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed